The mechanisms that control how the two parental pronuclei fuse in the first mitosis of the embryo are poorly understood. In this issue, Rahman et al. (2020. J. Cell Biol.https://doi.org/10.1083/jcb.201909137) found that membrane fusion between pronuclear envelopes, followed by fenestration, promotes pronuclear fusion.

中文翻译：

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膜融合驱动单细胞胚胎中的原核相遇


人们对胚胎第一次有丝分裂中两个亲本原核如何融合的控制机制知之甚少。在本期中，拉赫曼等人。 (2020. J. Cell Biol.https://doi.org/10.1083/jcb.201909137)发现原核包膜之间的膜融合，然后开窗，促进原核融合。