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NuMA1 facilitates the assembly of the axon initial segment by promoting the retention of neurofascin-186
Journal of Cell Biology ( IF 7.4 ) Pub Date : 2020-01-21 , DOI: 10.1083/jcb.201911139
Amr Abouelezz , Pirta Hotulainen 1
Affiliation  

Axon initial segment (AIS) functionality relies on a specific organization of the AIS with high enrichment of structural and functional proteins. In this issue, Torii et al. (2019. J. Cell. Biol.https://doi.org/10.1083/jcb.201907048) describe a mechanism for achieving a high density of proteins in the nascent AIS.

中文翻译:


NuMA1 通过促进 Neurofascin-186 的保留来促进轴突起始段的组装



轴突初始段 (AIS) 功能依赖于 AIS 的特定组织,具有高度富集的结构和功能蛋白。在本期中,Torii 等人。 (2019. J. Cell. Biol.https://doi.org/10.1083/jcb.201907048) 描述了一种在新生 AIS 中实现高密度蛋白质的机制。
更新日期:2020-01-21
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