Background An efficient biodegradation-strengthening approach was developed to improve penicillin G degradation from industrial bacterial residue in an expanded bed adsorption bioreactor (EBAB) is reported in this paper. Results Paracoccus sp. strain KDSPL-02 was isolated based on its ability to use penicillin G as the sole carbon and nitrogen source. Strain identification was based on analyses of morphology, physio-biochemical characteristics, and 16S rDNA sequences. The effects of temperature, pH, PVA-sodium alginate concentration, calcium chloride concentration and initial penicillin G concentration were investigated. Repeated operations of immobilized cells with EBAB, At initial penicillin concentrations below 2.0 g L- 1, the continuous mode could reach more than 20 times, and the degradation rate reached 100%. Conclusions The present study suggests that the EBAB system can be utilized for the simple and economical biodegradation of penicillin G from industrial bacterial residue.

中文翻译：

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副球菌固定化细胞对工业细菌残渣中青霉素 G 的生物降解作用 KDSPL-02通过连续膨胀床吸附生物反应器。

背景 本文报道了一种有效的生物降解强化方法，以改善在膨胀床吸附生物反应器 (EBAB) 中工业细菌残渣中青霉素 G 的降解。结果副球菌属。菌株 KDSPL-02 是基于其使用青霉素 G 作为唯一碳源和氮源的能力而分离出来的。菌株鉴定基于对形态学、生理生化特征和 16S rDNA 序列的分析。研究了温度、pH、PVA-海藻酸钠浓度、氯化钙浓度和初始青霉素G浓度的影响。EBAB固定化细胞反复操作，在初始青霉素浓度低于2.0 g L-1时，连续模式可达到20次以上，降解率达到100%。