Treatment of type 1 diabetes with insulin injection is expensive, complicated, and insufficient. While cadaveric islet transplantations coupled with immunosuppressants can cure diabetes, the scarcity of acceptable islets is problematic. Developmental research on pancreas formation has informed in vitro differentiation of human pluripotent stem cells into functional islets. Although generating β cells from stem cells offers a potential cure for type 1 diabetes, several challenges remain, including protecting the cells from the immune system.

中文翻译：

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一种治疗 1 型糖尿病的干细胞方法。

用胰岛素注射治疗 1 型糖尿病昂贵、复杂且效果不佳。虽然尸体胰岛移植加上免疫抑制剂可以治愈糖尿病，但可接受胰岛的稀缺是个问题。胰腺形成的发展研究为人类多能干细胞体外分化为功能性胰岛提供了信息。尽管从干细胞中产生 β 细胞为 1 型糖尿病提供了一种潜在的治疗方法，但仍存在一些挑战，包括保护细胞免受免疫系统的影响。