The majority of influenza A virus strains are hosted in nature by avian species in the orders of Anseriformes and Charadriformes. A minority of strains have been able to cross species boundaries and establish themselves in novel non-avian hosts. Influenza viruses of horses, donkeys, and mules represent such successful events of avian to mammal influenza virus adaptation. Mongolia has over 3 million domestic horses and is home to two wild equids, the Asiatic wild ass or khulan (Equus hemionus hemionus), and Przewalski's horse (Equus ferus przewalskii). Domestic and wild equids are sympatric across most of their range in Mongolia. Epizootic influenza A virus outbreaks among Mongolian domestic horses have been frequently recorded. However, the exposure, circulation and relation to domestic horse influenza A virus outbreaks among wild equids is unknown. We evaluated serum samples of Asiatic wild asses in Mongolia for antibodies against influenza A viruses, using modified protein microarray technique. We detected antibodies against hemagglutinin (H) H1, H3, H5, H7, H8 and H10 influenza A viruses. Asiatic wild asses may represent a previously unidentified influenza A virus reservoir in an ecosystem shared with populations of domestic horses in which influenza strains circulate.

中文翻译：

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首当其冲：蒙古胡兰（Equus hemionus hemionus）暴露于多种甲型流感病毒株。

自然界中，大多数甲型流感病毒株是由禽类寄养，其形式为Anseriformes和Charadriformes。少数菌株已经能够越过物种边界并在新型非禽类宿主中建立自己的地位。马，驴和mu子的流感病毒代表了禽类对哺乳动物流感病毒适应的成功事件。蒙古拥有超过300万匹家养马匹，并拥有两个野生马匹，即亚洲野驴或呼兰（Equus hemionus hemionus）和普氏原羚的马（Equus ferus przewalskii）。在蒙古的大部分范围内，家养和野生动物都是同胞。蒙古家养马中经常爆发流行性甲型流感病毒。但是，曝光 野马中的甲型H1N1流感流行及其与家庭马流感的关系尚不清楚。我们使用改良的蛋白质微阵列技术评估了蒙古亚洲野生驴血清样品中针对甲型流感病毒的抗体。我们检测到针对血凝素（H）H1，H3，H5，H7，H8和H10甲型流感病毒的抗体。亚洲野驴可能代表了一个生态系统中以前未知的甲型流感病毒库，该系统与流行流感株的家养马群共享。