In a previous sham-controlled study, we showed the feasibility of increasing language comprehension in healthy participants by applying anodal transcranial direct current stimulation (atDCS) over the left inferior frontal gyrus (LIFG). In the present work, we present a follow-up experiment targeting with atDCS the left inferior parietal cortex (LIPC) while participants performed the same auditory comprehension task used in our previous experiment. Both neural sites (LIFG and LIPC) are crucial hubs of Baddeley's model of verbal short-term memory (vSTM). AtDCS over LIPC decreased accuracy as compared to sham and LIFG stimulation, suggesting the involvement of this area in sentence comprehension. Crucially, our results highlighted that applying tDCS over different hubs of the same neural network can lead to opposite behavioural results, with relevant implications from a clinical perspective.

中文翻译：

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注意刺激部位：使用阳极 tDCS 增强和减弱句子理解

在之前的假手术对照研究中，我们展示了通过在左侧额下回 (LIFG) 上应用阳极经颅直流电刺激 (atDCS) 来提高健康参与者语言理解能力的可行性。在目前的工作中，我们提出了一项针对 atDCS 左下顶叶皮层 (LIPC) 的后续实验，而参与者执行了我们之前实验中使用的相同听觉理解任务。两个神经部位（LIFG 和 LIPC）都是 Baddeley 语言短期记忆模型 (vSTM) 的重要枢纽。与假刺激和 LIFG 刺激相比，LIPC 上的 AtDCS 降低了准确性，表明该区域参与了句子理解。至关重要的是，我们的结果强调，将 tDCS 应用于同一神经网络的不同中心会导致相反的行为结果，