Gastrointestinal (GI) disorders including a wide range of infectious, inflammatory, autoimmune, etc. disorders. Inflammatory bowel and celiac disease are non-fatal but overwhelming GI associated disorders. IBD and celiac's complications, besides the great suffering, disturb the normal life of the patients and make them involved in mental and physical problems. The emerging role of genetic content is deniable for GI inflammatory disorders incidence, and long non-coding RNAs (lncRNAs) function is the recent topic for its association. Analyzing of absolute lncRNAs interference in GI inflammatory appearance remains in infancy, and more studies are requested. Here, we concisely performed a systematic review in the last knowledge up to 2020 to identify all of the significant lncRNAs associated with the initiation and progression of GI inflammatory diseases. Accordingly, this assay attempted to refer to the expression of lncRNAs changing from the normal state, discovery of genetic mechanisms, and main effectors that would trigger associated IBD and celiac expression and immune responses would be effective for therapeutic approaches. It could be useful for prognostic and diagnostic purposes of GI associated inflammatory disorders.

中文翻译：

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长期的非编码RNA参与胃肠道相关的炎症性疾病。

胃肠道（GI）疾病，包括多种感染性，炎性，自身免疫性疾病。炎症性肠和腹腔疾病是非致命性的但与胃肠道疾病有关的疾病。IBD和腹腔疾病的并发症，除了带来巨大的痛苦之外，还扰乱了患者的正常生活，并使他们陷入精神和身体问题。遗传含量的新兴作用对于胃肠道炎症性疾病的发生是可取的，长的非编码RNA（lncRNA）功能是其关联的最新主题。在婴儿期，分析绝对的lncRNAs干扰GI炎症仍然存在，需要进行更多的研究。这里，我们简明扼要地对截至2020年的最新知识进行了系统的综述，以鉴定与胃肠炎性疾病的发生和发展相关的所有重要lncRNA。因此，该测定法试图参考从正常状态改变的lncRNA的表达，遗传机制的发现以及将触发相关IBD和腹腔表达以及免疫应答的主要效应子对于治疗方法将是有效的。它可用于胃肠道相关性炎性疾病的预后和诊断目的。触发相关IBD和腹腔表达以及免疫应答的主要效应器对于治疗方法将是有效的。它可用于胃肠道相关性炎性疾病的预后和诊断目的。触发相关IBD和腹腔表达以及免疫应答的主要效应器对于治疗方法将是有效的。它可用于胃肠道相关性炎性疾病的预后和诊断目的。