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Geographical distribution and prevalence of tick-borne encephalitis virus in questing Ixodes ricinus ticks and phylogeographic structure of the Ixodes ricinus vector in Norway.
Zoonoses and Public Health ( IF 2.4 ) Pub Date : 2020-02-29 , DOI: 10.1111/zph.12696
Rose Vikse 1 , Katrine M Paulsen 1, 2 , Kristin Skarsfjord Edgar 3 , John H-O Pettersson 4, 5, 6 , Preben Skrede Ottesen 3 , Yohannes Bein Okbaldet 1 , Nosheen Kiran 1 , Alaka Lamsal 1, 7 , Heidi Elisabeth H Lindstedt 3 , Benedikte Nevjen Pedersen 1, 7 , Arnulf Soleng 3 , Åshild K Andreassen 1, 7
Affiliation  

The tick-borne encephalitis virus (TBEV), a zoonotic flaviviral infection, is endemic in large parts of Norway and Eurasia. Humans are mainly infected with TBEV via bites from infected ticks. In Norway, the main geographical distribution of ticks is along the Norwegian coastline from southeast (~59°N) and up to the southern parts of Nordland County (~65°N). In this study, we collected ticks by flagging along the coast from Østfold County to Nordland County. By whole-genome sequencing of the mitochondrial genome of Ixodes ricinus, the phylogenetic tree suggests that there is limited phylogeographic structure both in Norway and in Europe. The overall TBEV prevalence is 0.3% for nymphs and 4.3% for adults. The highest estimated TBEV prevalence in adult ticks was detected in Rogaland and Vestfold County, while for nymphs it is highest in Vestfold, Vest-Agder and Rogaland. The present work is one of the largest studies on distribution and prevalence of TBEV in ticks in Scandinavia, showing that the virus is wider distributed in Norway than previously anticipated.

中文翻译:

挪威询问tick传播的脑炎病毒的地理分布和流行情况,以及x传播的cephal虫的地理结构。

Norway传播的脑炎病毒(TBEV)是一种人畜共患的黄病毒感染,在挪威和欧亚大陆的大部分地区为地方性流行。人类主要是通过被感染的s叮咬而感染TBEV。在挪威,壁虱的主要地理分布是沿着东南部(〜59°N)的挪威海岸线一直到诺德兰县的南部(〜65°N)的南部地区。在这项研究中,我们通过沿ØstfoldCounty到Nordland County的沿海地区进行旗标来收集tick。通过对蓖麻短线虫线粒体基因组的全基因组测序,系统进化树表明挪威和欧洲的植物地理结构有限。若虫的总体TBEV患病率为0.3%,成人为4.3%。在Rogaland和Vestfold县发现成年s中TBEV流行率最高,而若虫在Vestfold中则最高,背心-阿格德和罗加兰。目前的工作是对斯堪的那维亚tick中TBEV分布和流行的最大研究之一,表明该病毒在挪威的分布比以前预期的要广泛。
更新日期:2020-02-29
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