Ischemic stroke is a rare complication of varicella-zoster virus (VZV) infection. We present the case of a patient with a medical history of type 2 diabetes mellitus (DM) who experienced disseminated cutaneous VZV infection followed by multiple cerebral infarcts associated with VZV vasculopathy. Brain magnetic resonance imaging revealed multiple hyperintense lesions over the bilateral deep white matter and basal ganglia. A skin biopsy revealed small-vessel leukocytoclastic vasculitis with neutrophilic, lymphocytic, and eosinophilic infiltration. This case report describes the rare finding of cutaneous leukocytoclastic vasculitis in VZV infection and highlights that VZV infection is an uncommon but critical etiology of cryptogenic stroke in patients with DM.

中文翻译：

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成人糖尿病患者播散性皮肤带状疱疹和多发性脑梗塞。

缺血性中风是水痘-带状疱疹病毒 (VZV) 感染的一种罕见并发症。我们介绍了一例有 2 型糖尿病 (DM) 病史的患者，该患者经历了播散性皮肤 VZV 感染，随后发生与 VZV 血管病变相关的多发性脑梗塞。脑磁共振成像显示双侧深部白质和基底节多处高信号病变。皮肤活检显示小血管白细胞破碎性血管炎伴有中性粒细胞、淋巴细胞和嗜酸性粒细胞浸润。该病例报告描述了 VZV 感染中罕见的皮肤白细胞破碎性血管炎的发现，并强调 VZV 感染是 DM 患者隐源性卒中的一种罕见但重要的病因。