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Differential Behavioral and Neural Profiles in Youth With Conduct Problems During Risky Decision-Making.
Journal of Research on Adolescence ( IF 4.6 ) Pub Date : 2020-02-07 , DOI: 10.1111/jora.12546
Jorien van Hoorn 1 , Ethan M McCormick 1 , Michael T Perino 2 , Christina R Rogers 3 , Eva H Telzer 1
Affiliation  

Neuroimaging work has examined neural processes underlying risk taking in adolescence, yet predominantly in low‐risk youth. To determine whether we can extrapolate from current neurobiological models, this functional magnetic resonance imaging study investigated risk taking and peer effects in youth with conduct problems (CP; N = 19) and typically developing youth (TD; N = 25). Results revealed higher real‐life risk taking, lower risky decisions, and no peer effects on a risk‐taking task in CP youth. CP youth showed greater ventral striatum (VS) activity during safe than risky decisions, whereas TD youth showed greater VS activation during risky decisions. Differential VS activity explained higher real‐life risk taking in CP youth. Findings provide preliminary evidence that risk‐taking behavior in youth with CD problems is characterized by differential neural patterns.

中文翻译:

在风险决策期间有行为问题的青年的不同行为和神经特征。

神经影像学工作已经检查了青少年冒险的神经过程,但主要是在低风险青年中。为了确定我们是否可以从当前的神经生物学模型中推断,这项功能性磁共振成像研究调查了有行为问题的青年(CP;N  = 19)和典型的发展中青年(TD;N )的风险承担和同伴影响。 = 25)。结果显示,在 CP 青年中,现实生活中的风险承担更高,风险决策更低,并且对冒险任务没有同伴影响。CP 青年在安全决策期间表现出比风险决策更大的腹侧纹状体 (VS) 活动,而 TD 青年在风险决策期间表现出更大的 VS 激活。差异 VS 活动解释了 CP 青年在现实生活中承担更高的风险。研究结果提供了初步证据,表明患有 CD 问题的青年的冒险行为具有不同的神经模式特征。
更新日期:2020-02-07
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