Colonic atresias in the Fibroblast growth factor receptor 2IIIb (Fgfr2IIIb) mouse model have been attributed to increased epithelial apoptosis and decreased epithelial proliferation at embryonic day (E) 10.5. We therefore hypothesized that these processes would colocalize to the distal colon where atresias occur (atretic precursor) and would be excluded or minimized from the proximal colon and small intestine.

中文翻译：

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在成纤维细胞生长因子受体 2IIIb 小鼠的结肠中，缺乏上皮细胞凋亡与闭锁前体的谨慎共定位，并且染色与细胞运动一致，表明闭锁形成模型的修正。


成纤维细胞生长因子受体 2IIIb (Fgfr2IIIb)小鼠模型中的结肠闭锁归因于胚胎日 (E) 10.5 时上皮细胞凋亡增加和上皮增殖减少。因此，我们假设这些过程将共定位于发生闭锁的远端结肠（闭锁前兆），并且会被近端结肠和小肠排除或最小化。