Background: In more than 10% of emergency laparotomies in non-trauma patients, primary fascial closure is not achievable because of excessive visceral edema, which leaves the patient with an open abdomen (OA). An OA harbors an inherent high risk of serious complications, and temporary closure devices are used to achieve delayed fascial closure. A potential new strategy in preventing OA is immediate closure during the emergency procedure with a non-crosslinked biologic mesh.

中文翻译：

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在非创伤急诊患者中使用生物网立即关闭腹腔与暂时关闭开放腹腔（CLOSE-UP 研究）。

背景：在超过 10% 的非创伤患者的急诊剖腹手术中，由于过度的内脏水肿而无法实现初级筋膜闭合，从而使患者出现开腹（OA）。OA 存在严重并发症的固有高风险，临时闭合装置用于实现延迟筋膜闭合。预防 OA 的潜在新策略是在紧急手术期间使用非交联生物网立即闭合。