This review summarizes progress in understanding electron transfer from photoexcited nanocrystals to redox enzymes. The combination of the light-harvesting properties of nanocrystals and the catalytic properties of redox enzymes has emerged as a versatile platform to drive a variety of enzyme-catalyzed reactions with light. Transfer of a photoexcited charge from a nanocrystal to an enzyme is a critical first step for these reactions. This process has been studied in depth in systems that combine Cd-chalcogenide nanocrystals with hydrogenases. The two components can be assembled in close proximity to enable direct interfacial electron transfer or integrated with redox mediators to transport charges. Time-resolved spectroscopy and kinetic modeling have been used to measure the rates and efficiencies of the electron transfer. Electron transfer has been described within the framework of Marcus theory, providing insights into the factors that can be used to control the photochemical activity of these biohybrid systems. The range of potential applications and reactions that can be achieved using nanocrystal-enzyme systems is expanding, and numerous fundamental and practical questions remain to be addressed.

中文翻译：

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电子从半导体纳米晶体转移到氧化还原酶。

这篇综述总结了在理解从光激发纳米晶体到氧化还原酶的电子转移方面的进展。纳米晶体的光收集特性与氧化还原酶的催化特性的结合已经成为驱动多种酶催化光反应的通用平台。将光激发电荷从纳米晶体转移至酶是这些反应的关键第一步。在将Cd-硫族化物纳米晶体与氢化酶结合的系统中，对该过程进行了深入研究。这两个组件可以紧密组装在一起，以实现直接的界面电子转移，也可以与氧化还原介体集成在一起以传输电荷。时间分辨光谱法和动力学建模已用于测量电子转移的速率和效率。已经在马库斯理论的框架内描述了电子转移，从而提供了可用于控制这些生物杂交系统光化学活性的因素的见解。使用纳米晶体酶系统可以实现的潜在应用和反应范围正在扩大，许多基本和实际问题仍有待解决。