There are different varieties of mushrooms not yet studied spread all over the planet. The objective of this study was to evaluate biochemical properties and effects on mitochondrial respiration of eight Basidiomycete mushrooms: Flaviporus venustus EF30, Hydnopolyporus fimbriatus EF41 and EF44, Inonotus splitgerberi EF46, Oudemansiella canarii EF72, Perenniporia sp. EF79, Phellinus linteus EF81, and Pleurotus albidus EF84. Total phenols, ABTS, TEAC, FRAP, and ORAC were measured in order to determine the antioxidant capacity. Antimicrobial potential was studied by disc-diffusion and microdilution method. Cytotoxicity was determined in murine peritoneal macrophages. The bioenergetic aspects were evaluated by the uncoupling of the oxidative phosphorylation in mitochondrias. The H. fimbriatus mushroom was the one that presented the most significant results for the antioxidant assays. Three mushrooms presented antimicrobial activity, indicating a potential for formulation of drugs. The results suggest that I. spligerberi has an uncoupling activity, even at the lowest concentration tested, dissipating the mitochondrial electrochemical gradient. On the other hand, P. albidus has effect only on succinate-oxidase activity without influencing mitochondrial respiratory efficiency. Therefore, both interfere negatively in mitochondrial respiration. In relation with the cytotoxicity in peritoneal macrophages, O. canarii and F. venustus were cytotoxic in this type of cells.

中文翻译：

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担子菌蘑菇水提物的生化特性及其对线粒体呼吸的影响。

尚未研究的蘑菇种类繁多，遍及全球。这项研究的目的是评估八种担子菌蘑菇的生化特性及其对线粒体呼吸的影响：Flaviporus venustus EF30，Hydnopolyporus fimbriatus EF41和EF44，Inonotus splitgerberi EF46，Oudemansiella canarii EF72，Perenniporia sp。EF79，桑黄EF81和白灵菇EF84。测量总酚，ABTS，TEAC，FRAP和ORAC，以确定抗氧化能力。通过盘扩散和微量稀释法研究了抗菌潜力。测定了小鼠腹膜巨噬细胞的细胞毒性。通过线粒体中氧化磷酸化的解偶联来评估生物能方面。该H. fimbriatus蘑菇是一个提出了抗氧化试验最显著的效果。三个蘑菇具有抗菌活性，表明可能具有药物开发的潜力。结果表明，即使在最低测试浓度下，S。spligerberi也具有解偶联活性，从而消除了线粒体的电化学梯度。另一方面，P。albidus仅对琥珀酸氧化酶活性有影响，而不会影响线粒体呼吸效率。因此，两者都不利地影响线粒体呼吸。与腹膜巨噬细胞细胞毒性的关系，O.青果和F. venustus是在这种类型的细胞的细胞毒性的。