BACKGROUND The influence of socioeconomic status on patient outcomes is unclear. We assessed the impact of socioeconomic deprivation on severity of illness at intensive care unit (ICU) admission, and on the risk of death at 3 months after ICU admission. METHODS The IVOIRE study was a prospective, observational, multicentre cohort study in the ICU of 8 participating hospitals in France, including patients aged ≥ 18 years admitted to the ICU and receiving at least one life support therapy for organ failure. The primary outcomes were severity at admission (assessed by SAPSII score), and mortality at 3 months. Socioeconomic data were obtained from interviews with patients or family. Deprivation was assessed using the EPICES score. RESULTS Among 1294 patents included between 2013 and 2016, 629 (48.6%) were classed as deprived and differed significantly from non-deprived subjects in terms of sociodemographic characteristics and pre-existing conditions. The mean SAPS II score at admission was 50.1 ± 19.4 in deprived patients and 52.3 ± 17.3 in non-deprived patients, with no significant difference by multivariable analysis (β = - 1.85 [95% CI - 3.86; + 0.16, p = 0.072]). The proportion of death was 31.1% at 3 months, without significant differences between deprived and non-deprived patients, even after adjustment for confounders. CONCLUSIONS Deprivation is frequent in patients admitted to the ICU and is not associated with disease severity at admission, or with mortality at 3 months between deprived and non-deprived patients. Trial registration The IVOIRE cohort is registered with ClinicalTrials.gov under the identifier NCT01907581, registration date 17/7/2013.

中文翻译：

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剥夺对入住ICU的患者的严重程度和预后的影响：前瞻性，多中心，观察性IVOIRE队列研究。

背景技术社会经济状况对患者预后的影响尚不清楚。我们评估了社会经济剥夺对重症监护病房（ICU）入院时疾病严重程度以及入ICU 3个月后死亡风险的影响。方法IVOIRE研究是在法国8所参与医院的ICU中进行的一项前瞻性，观察性，多中心队列研究，其中包括≥18岁的ICU住院患者，并接受了至少一种因器官衰竭而接受的生命支持治疗。主要结果是入院时的严重程度（通过SAPSII评分评估）和3个月时的死亡率。社会经济数据来自对患者或家庭的访谈。使用EPICES评分评估剥夺。结果2013年至2016年期间，共有1294项专利，其中629项（48。6％）被归类为被剥夺者，在社会人口统计学特征和既往条件方面与非被剥夺者有显着差异。贫困患者入院时平均SAPS II评分为50.1±19.4，非贫困患者为52.3±17.3，通过多变量分析无显着差异（β=-1.85 [95％CI-3.86； + 0.16，p = 0.072] ）。3个月时的死亡比例为31.1％，即使对混杂因素进行调整后，贫困患者和非贫困患者之间也没有显着差异。结论在ICU收治的患者中剥夺频繁，与入院时的疾病严重程度无关，也与剥夺和未剥夺患者之间3个月的死亡率无关。试验注册IVOIRE队列已在ClinicalTrials.gov上以标识符NCT01907581注册，