Damage to skin tissue, which causes the disorder of the patient's body homeostasis, threatens the patient's life and increases the personal and social treatment burden. Angiogenesis, a key step in the wound healing process, provides sufficient oxygen and nutrients to the wound area. However, traditional clinical interventions are not enough to stabilize the formation of the vascular system to support wound healing. Due to the unique properties and multiple functions of nanomaterials, it has made a major breakthrough in the application of medicine. Nanomaterials provide a more effective treatment to hasten the angiogenesis and wound healing, by stimulating fundamental factors in the vascular regeneration phase. In the present review article, the basic stages and molecular mechanisms of angiogenesis are analyzed, and the types, applications, and prospects of nanomaterials used in angiogenesis are detailed.

中文翻译：

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皮肤组织工程中用于血管生成的纳米材料。

对皮肤组织的损害导致患者体内稳态的紊乱，威胁患者的生命并增加个人和社会治疗负担。血管生成是伤口愈合过程中的关键步骤，可为伤口区域提供足够的氧气和营养。然而，传统的临床干预措施不足以稳定血管系统的形成以支持伤口愈合。由于纳米材料的独特性能和多种功能，在医学应用上取得了重大突破。纳米材料通过刺激血管再生阶段的基本因素，提供了一种更有效的治疗方法，可加快血管生成和伤口愈合。在本篇综述文章中，分析了血管生成的基本阶段和分子机制，以及类型，应用，