Natural Products (NP), specifically from medicinal plants or herbs, have been extensively utilized to analyze the fundamental mechanisms of ultimate natural sciences as well as therapeutics. Isolation of secondary metabolites from these sources and their respective biological properties, along with their lower toxicities and cost-effectiveness, make them a significant research focus for drug discovery. In recent times, there has been a considerable focus on isolating new chemical entities from natural flora to meet the immense demand for kinase modulators, and also to overcome major unmet medical challenges in relation to signal transduction pathways. The signal transduction systems are amongst the foremost pathways involved in the maintenance of life and protein kinases play an imperative part in these signaling pathways. It is important to find a kinase inhibitor, as it can be used not only to study cell biology but can also be used as a drug candidate for cancer and metabolic disorders. A number of plant extracts and their isolated secondary metabolites such as flavonoids, phenolics, terpenoids, and alkaloids have exhibited activities against various kinases. In the current review, we have presented a brief overview of some important classes of plant secondary metabolites as kinase modulators. Moreover, a number of phytocompounds with kinase inhibition potential, isolated from different plant species, are also discussed.

天然产物（NP），特别是药用植物或草药的天然产物，已被广泛用于分析最终自然科学和治疗方法的基本机理。从这些来源中分离次生代谢产物及其各自的生物学特性，以及较低的毒性和成本效益，使其成为药物发现的重要研究重点。近年来，人们非常关注从天然菌群中分离出新的化学实体，以满足对激酶调节剂的巨大需求，并克服与信号转导途径有关的重大未满足的医学挑战。信号转导系统是维持生命的最重要途径之一，蛋白激酶在这些信号通路中起着必不可少的作用。找到一种激酶抑制剂非常重要，因为它不仅可以用于研究细胞生物学，还可以用作癌症和代谢性疾病的候选药物。许多植物提取物及其分离的次级代谢产物，如黄酮类，酚类，萜类和生物碱，均表现出针对各种激酶的活性。在当前的审查中，我们已经简要概述了一些重要的植物次生代谢产物作为激酶调节剂。此外，还讨论了从不同植物物种中分离出来的许多具有激酶抑制潜能的植物化合物。萜类和生物碱对各种激酶均具有活性。在当前的审查中，我们已经简要概述了一些重要的植物次生代谢产物作为激酶调节剂。此外，还讨论了从不同植物物种中分离出来的许多具有激酶抑制潜能的植物化合物。萜类和生物碱对各种激酶均具有活性。在当前的审查中，我们已经简要概述了一些重要的植物次生代谢产物作为激酶调节剂。此外，还讨论了从不同植物物种中分离出来的许多具有激酶抑制潜能的植物化合物。