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Persistent Urinary Ethyl Sulfate in the Absence of Urinary Ethyl Glucuronide in a Patient with Alcohol Use Disorder Who Claimed Abstinence.
Journal of Analytical Toxicology ( IF 2.5 ) Pub Date : 2020-02-24 , DOI: 10.1093/jat/bkaa014
Gary M Reisfield 1 , Scott A Teitelbaum 2 , Joseph T Jones 3
Affiliation  

A 48-year-old nurse with an alcohol use disorder history was being monitored in a professional health program. She consistently produced low-to-moderate urinary ethyl sulfate (EtS) concentrations in the absence of detectable urinary ethyl glucuronide (EtG), blood phosphatidylethanol and breath alcohol. She denied intentional ethanol consumption. After prolonged monitoring in a drug treatment program, including a period in a controlled environment, we concluded that this individual’s urinary EtS likely resulted from anatomical and microbial factors related to Roux-en-Y gastric bypass surgery, with possible contributions from hidden dietary sources of ethanol. We have no definitive explanation for the lack of urinary EtG.

中文翻译:

声称戒酒的酒精使用障碍患者的尿乙基葡萄糖醛酸苷缺乏的持续性尿硫酸乙酯。

在专业健康计划中对一名48岁有酗酒史的护士进行了监测。在没有可检测到的尿乙基葡糖醛酸苷(EtG),血液磷脂酰乙醇和呼吸酒精的情况下,她始终产生低至中度的尿硫酸乙酯(EtS)浓度。她否认有意饮酒。在药物治疗计划中进行了长期监测(包括在受控环境中的一段时间)后,我们得出结论,该人的尿EtS可能是由于与Roux-en-Y胃搭桥手术相关的解剖学和微生物因素造成的,并且可能来自隐性饮食来源乙醇。对于缺乏尿EtG,我们没有确切的解释。
更新日期:2020-02-24
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