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Molecular genetic analysis and clinical characterization of Rickettsia species isolated from the Republic of Korea in 2017.
Transboundary and Emerging Diseases ( IF 4.3 ) Pub Date : 2020-02-23 , DOI: 10.1111/tbed.13525
Yeon-Sook Kim 1 , Jeoungyeon Kim 2, 3 , Yeon-Joo Choi 2, 3 , Hye-Jin Park 2, 3 , Won-Jong Jang 2, 3
Affiliation  

Rickettsia sp. CNH17‐7 was isolated from patients' blood and identified by gene analysis as a species distinct from Rickettsia japonica . In addition, similar rickettsial infection was confirmed in two species (Haemaphysalis longicornis and Ixodes nipponensis ) of ticks and rodents in northeastern and southwestern provinces, Republic of Korea. Subsequently, the analysis of 16S rRNA, ompA , ompB and sca4 genes of isolate CNH17‐7 revealed 100%, 99.68%, 99.57% and 99.44% sequence similarity with Rickettsia sp. HlR/D91 and Candidatus R. longicornii ROK‐HL727. In this study, we report the isolation of a new Rickettsia sp. CNH17‐7 and infection of different types of ticks with the same rickettsial agents.

中文翻译:

2017年从大韩民国分离到的立克次体物种的分子遗传学分析和临床表征。

立克次氏体属。CNH17-7是从患者血液中分离出来的,并通过基因分析鉴定为不同于日本立克次体的物种。此外,在大韩民国的东北和西南省,在tick和啮齿动物的两个物种(Haemaphysalis longicornisIxodes nipponensis)中证实了相似的立克次氏体感染。随后,对分离出的CNH17-7的16S rRNA,ompAompBsca4基因的分析显示与立克次体菌100%,99.68%,99.57%和99.44%的序列相似性。HLR / D91和暂定R. longicornii ROK-HL727。在这项研究中,我们报告了新立克次氏体属。CNH17-7和使用相同的立克次体感染不同类型的虱子。
更新日期:2020-02-23
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