Uveitis (JIA-U), the most common extra-articular manifestation in juvenile idiopathic arthritis (JIA), may cause severe impairment of vision in children and affect their quality of life (QoL). Considering the lack of uveitis-related QoL assessment questionnaire, and multidimensional nature of the Juvenile Arthritis Multidimensional Assessment Report (JAMAR), commonly used for monitoring and assessing the health status of children with JIA, we performed a cross-sectional study to investigate the potential of the JAMAR in estimation of QoL in children suffering from JIA-U. The study included 42 children with JIA, 21 of whom had JIA-U. Both children and their parents completed the JAMAR. We compared two groups of children (JIA-U and JIA without uveitis) and their parents against five extracted questionnaires items (QoL, functional ability, pain level, disease activity estimation, and current emotional state of the child) using the independent-samples t test to verify the differences and the Pearson correlation coefficient to measure the strength of a linear association between variables. No significant statistical difference in any of the examined variables was found between the two groups of children. In the groups of parents, current emotional state of children with JIA-U was assessed to be significantly worse (t = 2.05, p < 0.05) and the overall level of functioning significantly lower (t = 2.03, p < 0.05) than children without uveitis. Our results suggest the need for adding the uveitis-specific questionnaires items to JAMAR to improve its sensitivity and specificity in the assessment of QoL in children suffering from JIA-U, as well as designing a second assessment tool such as uveitis-specific questionnaires.

中文翻译：

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患幼年特发性关节炎相关葡萄膜炎的儿童的生活质量。

葡萄膜炎（JIA-U）是青少年特发性关节炎（JIA）中最常见的关节外表现，可能导致儿童视力严重受损并影响其生活质量（QoL）。考虑到缺乏与葡萄膜炎相关的QoL评估问卷，以及通常用于监测和评估JIA儿童健康状况的《青少年关节炎多维评估报告》（JAMAR）的多维性质，我们进行了一项横断面研究以调查潜在的JAMAR在评估JIA-U患儿的QoL中的作用。该研究纳入了42名患有JIA的儿童，其中21名患有JIA-U。孩子和他们的父母都完成了JAMAR。我们比较了两组儿童（JIA-U和未患葡萄膜炎的JIA）及其父母与五个提取的问卷项目（QoL，功能能力，疼痛程度，使用独立样本t检验来验证差异，并使用Pearson相关系数来测量变量之间线性关联的强度。两组儿童之间在任何检查变量中均未发现统计学差异。在父母群体中，据评估，JIA-U患儿的当前情绪状态明显较未患JIA-U的患儿差（t = 2.05，p <0.05），总体功能水平显着降低（t = 2.03，p <0.05）。葡萄膜炎。我们的结果表明，有必要在JAMAR中添加针对葡萄膜的问卷，以提高其对JIA-U患儿QoL评估的敏感性和特异性，