Since the Syrian civil war in 2011, an estimated number of 3.6 million Syrian refugees crossed into Turkey, and almost half of them were children. The distribution of rheumatic diseases in Syrian refugee children is not known. The aim of this study was to describe the profile of rheumatic diseases in Syrian refugee children living in Turkey. The demographic data, clinical and laboratory findings, medications, complications and outcome results of Syrian refugee children who had visited Pediatric Rheumatology Departments of University of Health Science Kanuni Sultan Süleyman Research and Training Hospital, Ümraniye Research and Training Hospital, Şanlıurfa Research and Training Hospital, and Cengiz Gökçek Maternity and Gynecology Hospital between April 1, 2011, and September 1, 2019, were evaluated retrospectively. A total of 151 patients were included in the study. Among them, 51 patients had juvenile idiopathic arthritis (JIA), 49 had familial Mediterranean fever (FMF), 43 had vasculitis, and 8 had connective tissue diseases. Homozygous M694V mutation was the most common mutation among FMF patients. Oligoarticular JIA (41.2%) was the most frequent type of JIA, and enthesitis-related arthritis (ERA) (27.5%) was the second one. The frequency of systemic JIA was 11.8%. One patient with SLE died due to complicated meningitis. This is the first study evaluating the distribution of rheumatic diseases in Syrian refugee children. Clinical follow-up of rheumatologic diseases is difficult in Syrian refugees due to language barriers, social and cultural differences. Health care systems should be well organized to provide appropriate care to asylum seekers.

中文翻译：

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叙利亚难民儿童的风湿病：土耳其的一项多中心回顾性研究。

自2011年叙利亚内战以来，估计有360万叙利亚难民越境进入土耳其，其中近一半是儿童。叙利亚难民儿童中风湿病的分布情况尚不清楚。这项研究的目的是描述居住在土耳其的叙利亚难民儿童中的风湿病。访问健康科学大学卡努尼·苏丹·苏莱曼研究与培训医院，乌姆兰尼耶研究与培训医院，桑尼卢法研究与培训医院，对2011年4月1日至2019年9月1日期间的CengizGökçek妇产科医院进行了回顾性评估。该研究总共包括151名患者。其中，青少年特发性关节炎（JIA）51例，家族性地中海热（FMF）49例，血管炎43例，结缔组织病8例。纯合子M694V突变是FMF患者中最常见的突变。少关节型JIA（41.2％）是最常见的JIA类型，第二位是与炎症相关的关节炎（ERA）（27.5％）。系统性JIA的发生率为11.8％。一名SLE患者因复杂的脑膜炎死亡。这是第一项评估风湿性疾病在叙利亚难民儿童中的分布的研究。由于语言障碍，社会和文化差异，叙利亚难民很难对风湿病进行临床随访。卫生保健系统应组织得当，为寻求庇护者提供适当的照顾。