Gas gangrene is a necrotizing infection of subcutaneous tissue and muscle that affects mainly ruminants and horses, but also other domestic and wild mammals. Clostridium chauvoei, C. septicum, C. novyi type A, C. perfringens type A, and C. sordellii are the etiologic agents of this disease, acting singly or in combination. Although a presumptive diagnosis of gas gangrene can be established based on clinical history, clinical signs, and gross and microscopic changes, identification of the clostridia involved is required for confirmatory diagnosis. Gross and microscopic lesions are, however, highly suggestive of the disease. Although the disease has a worldwide distribution and can cause significant economic losses, the literature is limited mostly to case reports. Thus, we have reviewed the current knowledge of gas gangrene in mammals.

中文翻译：

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哺乳动物中的坏疽性气体：综述。

坏疽性气体坏死是皮下组织和肌肉的坏死性感染，主要感染反刍动物和马匹，但也影响其他家养和野生哺乳动物。梭状芽胞杆菌，败血梭状芽孢杆菌，诺维梭状芽胞杆菌A型，产气荚膜梭状芽孢杆菌和C. sordellii是该病的病原体，可单独或联合作用。尽管可以根据临床病史，临床体征以及肉眼和显微镜下的变化确定坏疽性坏疽的诊断，但对于确诊诊断，需要鉴定出所涉及的梭状芽胞杆菌。然而，肉眼和微观病变高度提示该病。尽管该病在世界范围内分布并可能造成重大的经济损失，但文献大多仅限于病例报告。因此，我们回顾了哺乳动物中气体坏疽的最新知识。