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Pharmacokinetics and pharmacodynamics of clodronate disodium evaluated in plasma, synovial fluid and urine.
Equine Veterinary Journal ( IF 2.4 ) Pub Date : 2020-01-31 , DOI: 10.1111/evj.13244
Clarisa R Krueger 1 , Colin F Mitchell 1 , Britta S Leise 1 , Heather K Knych 2
Affiliation  

Clodronate is a non‐nitrogenated bisphosphonate approved for use in horses. There are no peer‐reviewed published reports describing the pharmacokinetics or evaluating renal health indices and urinary excretion patterns in conjunction with plasma and synovial fluid concentration following the systemic administration of clodronate to horses.

中文翻译:

在血浆、滑液和尿液中评估氯膦酸二钠的药代动力学和药效学。

氯膦酸盐是一种批准用于马的非氮化双膦酸盐。没有经过同行评审的已发表报告描述氯膦酸盐全身给药后的药代动力学或评估肾脏健康指数和尿液排泄模式以及血浆和滑液浓度。
更新日期:2020-01-31
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