Smoking prevalence among those with alcohol dependence is much higher than the general population. Despite this, cessation treatment in those with concurrent alcohol dependence is seldom undertaken. We conducted a randomized, placebo-controlled, double-blind pilot study, whereby patients enrolled at an addiction treatment facility in downtown Toronto, Canada, were recruited and assigned to placebo or varenicline treatment for 12 weeks. We hypothesized that varenicline would be a safe and efficacious treatment for tobacco dependence in this population.

中文翻译：

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伐尼克兰在依赖酒精的吸烟者同时戒酒治疗中的安全性和有效性：一项随机安慰剂对照试验。

酒精依赖者的吸烟率远高于普通人群。尽管如此，很少有酒精依赖的人戒烟治疗。我们进行了一项随机，安慰剂对照，双盲先导研究，招募了在加拿大多伦多市中心的成瘾治疗设施中招募的患者，并将其分配给安慰剂或伐尼克兰治疗12周。我们假设伐尼克兰是该人群中烟草依赖的一种安全有效的治疗方法。