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An Open-Label Trial of Methylphenidate Treating Sluggish Cognitive Tempo, Inattention, and Hyperactivity/Impulsivity Symptoms Among 6- to 12-Year-Old ADHD Children: What Are the Predictors of Treatment Response at Home and School?
Journal of Attention Disorders ( IF 2.7 ) Pub Date : 2020-02-17 , DOI: 10.1177/1087054720902846
Sumeyra Fırat 1 , Hesna Gul 2 , Ayla Aysev 3
Affiliation  

Objective: This study investigated the effects of sluggish cognitive tempo (SCT), other psychiatric symptoms, age, dose, and pretreatment ADHD severity on methylphenidate (MPH) treatment response among ADHD children in both home and school. In addition, the predictors of the MPH-SCT treatment response were examined. Methods: One hundred eighty-five (6-12 years old) ADHD children who were treated with MPH included in the study. Results: MPH improved SCT total and SCT-Daydreaming scores both at home and school while improved SCT-Sluggish scores in only school. Higher pretreatment Daydreaming score predicted lower treatment response for inattention (B = .301, p = .002), and higher Daydreaming-Sluggish scores predicted lower treatment response for total ADHD symptoms at school (B = .456, p = .006; B = .888, p = .04, respectively). Also higher oppositional defiant disorder symptoms have negative effects on MPH treatment response in ADHD. Older age positively affected the MPH-SCT treatment response in paternal and teacher ratings. Conclusion: SCT symptoms have negative effects on MPH treatment response at school.

中文翻译:

哌醋甲酯治疗6至12岁多动症儿童迟钝的认知节奏,注意力不集中和过度活跃/冲动症状的开放标签试验:家庭和学校治疗反应的预测因素是什么?

目的:本研究调查了在家中和学校中多动症儿童的认知速度,其他精神症状,年龄,剂量和治疗前多动症严重程度对哌醋甲酯(MPH)治疗反应的影响。另外,检查了MPH-SCT治疗反应的预测因子。方法:本研究纳入了接受MPH治疗的185名(6-12岁)ADHD儿童。结果:MPH提高了家庭和学校的SCT总成绩和SCT白日梦得分,而仅在学校就提高了SCT懒惰得分。较高的治疗前白日梦得分预测了对注意力不集中的较低治疗反应(B = .301,p = .002),较高的Daydreaming-Sluggish得分预测了对学校总ADHD症状的较低治疗反应(B = .456,p = .006; B = .888,p = .04)。同样,较高的对立反抗障碍症状对ADHD中的MPH治疗反应也有负面影响。老年人对父亲和老师的评分对MPH-SCT治疗反应产生积极影响。结论:SCT症状对学校的MPH治疗反应有负面影响。
更新日期:2020-04-20
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