Background: Stroke is a major cause of life-long disability in adults, associated with poor quality of life. Virtual reality (VR)-based therapy systems are known to be helpful in improving motor functions following stroke, but recent clinical findings have not been included in the previous publications of meta-analysis studies.Aims: This meta-analysis was based on the available literature to evaluate the therapeutic potential of VR as compared to dose-matched conventional therapies (CT) in patients with stroke.Methods: We retrieved relevant articles in EMBASE, MEDLINE, PubMed, and Web of Science published between 2010 and February 2019. Peer-reviewed randomized controlled trials that compared VR with CT were included.Results: A total of 27 studies met the inclusion criteria. The analysis indicated that the VR group showed statistically significant improvement in the recovery of UL function (Fugl-Meyer Upper Extremity [FM-UE]: n = 20 studies, Mean Difference [MD] = 3.84, P = .01), activity (Box and Block Test [BBT]: n = 13, MD = 3.82, P = .04), and participation (Motor Activity Log [MAL]: n = 6, MD = 0.8, P = .0001) versus the control group.Conclusion: VR appears to be a promising therapeutic technology for UL motor rehabilitation in patients with stroke.

中文翻译：

---

中风患者上肢康复的虚拟现实疗法：随机临床试验的荟萃分析。

背景：中风是成年人终生残疾的主要原因，与生活质量差有关。众所周知，基于虚拟现实 (VR) 的治疗系统有助于改善中风后的运动功能，但最近的临床发现并未包含在先前发表的荟萃分析研究中。 目的：本荟萃分析基于现有的与剂量匹配的常规疗法 (CT) 相比，评估 VR 在卒中患者中的治疗潜力的文献。回顾了比较 VR 与 CT 的随机对照试验。结果：共有 27 项研究符合纳入标准。