Background: Evidence suggests lack of understanding of the association of specific nutrients with different time points of linear growth trajectory. Objective: We investigated the role of dietary macro- and micronutrients on length-for-age z (LAZ) score trajectory of children across first 24 months of their life. Methods: The MAL-ED Bangladesh birth cohort study recruited 265 healthy newborn children after birth. The linear growth trajectory of those children was modeled using latent growth curve modeling (LGCM) technique. Results: Dietary magnesium intake at 9 to 11 months was positively associated (coefficient β = 0.006, P < .02) with LAZ at 12 months. Animal protein intake at 15 to 17 months, in turn, was positively associated (β = 0.03, P < .03) with LAZ at 18 months. However, vitamin D intake at 15 to 17 months was negatively associated (β = −0.06, P < .02) with LAZ at 18 months. Other micro- and macronutrients did not show any statistically significant association with the linear growth trajectory. We also found that birth weight (β = 0.91, P < .01), treating water (β = 0.35, P < 0.00), and maternal height (β = 3.4, P < .00) were positively associated with intercept. Gender had a significant negative association with the intercept, but a positive association with the slope (β = −0.39, P < .01; β = 0.08, P < .04), respectively. Conversely, birth weight had negative association with the slope (β = −0.12, P < .01). Conclusions: Dietary magnesium and animal protein were positively and vitamin D was negatively associated with the linear growth trajectory. Maternal height, birth weight, gender, and treatment of drinking water also played significant roles in directing the trajectory.

中文翻译：

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膳食镁、维生素 D 和动物蛋白摄入量及其与从出生到 24 个月大的儿童线性生长轨迹的关联：来自在孟加拉国达卡进行的 MAL-ED 出生队列研究的结果

背景：有证据表明，缺乏对特定营养素与线性生长轨迹不同时间点的关联的了解。目标：我们调查了膳食宏量营养素和微量营养素对儿童生命前 24 个月的年龄别身长 z (LAZ) 评分轨迹的作用。方法：MAL-ED 孟加拉国出生队列研究招募了 265 名出生后健康的新生儿。这些儿童的线性生长轨迹是使用潜在生长曲线建模 (LGCM) 技术建模的。结果：9 至 11 个月的膳食镁摄入量与 12 个月的 LAZ 呈正相关（系数 β = 0.006，P < .02）。反过来，15 至 17 个月时动物蛋白的摄入量与 18 个月时的 LAZ 呈正相关（β = 0.03，P < .03）。然而，15 至 17 个月时维生素 D 的摄入量与 18 个月时的 LAZ 呈负相关（β = -0.06，P < .02）。其他微量营养素和常量营养素与线性生长轨迹没有任何统计学上的显着关联。我们还发现出生体重 (β = 0.91, P < .01)、处理水 (β = 0.35, P < 0.00) 和母亲身高 (β = 3.4, P < .00) 与截距呈正相关。性别与截距呈显着负相关，但与斜率呈正相关（β = -0.39，P < .01；β = 0.08，P < .04）。相反，出生体重与斜率呈负相关（β = -0.12，P < .01）。结论：膳食镁和动物蛋白与线性增长轨迹呈正相关，而维生素 D 与线性增长轨迹呈负相关。产妇身高、出生体重、性别、