当前位置: X-MOL 学术Crit. Rev. Anal. Chem. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Biological Properties and Analytical Methods for Micafungin: A Critical Review.
Critical Reviews in Analytical Chemistry ( IF 4.2 ) Pub Date : 2020-02-16 , DOI: 10.1080/10408347.2020.1726726
Gabriel Davi Marena 1 , Matheus Aparecido Dos Santos Ramos 1 , Taís Maria Bauab 1 , Marlus Chorilli 1
Affiliation  

Micafungin is characterized as one of the most active available drugs for candidemia treatment; however, their use is also associated in prophylaxis protocols in cases of invasive fungal infections. The use of this drug is widely appreciated in the medical field due to be the most active echinocandin available for invasive fungal infections. In order to provide important parameters related to the chemical, physical, biological and therapeutic characteristics, this review article gathers important research results that demonstrate the biological potential of this drug, as well as to present analytical methods that can be used to determine the antifungal potential and a monitoring of administered dosages. Important studies about the methods most commonly used in biological activity evaluation and determination/quantification by analytical methods are provided in this review article. With the data provided, the scientific community will have the possibility to choose the analytical methods and biological that can be employed in clinical and scientific research to provide greater safety and reliability of the results to be found.

中文翻译:

米卡芬净的生物学特性和分析方法:批判性评论。

米卡芬净是治疗念珠菌病最有效的药物之一;然而,它们的使用也与侵袭性真菌感染的预防方案有关。由于该药物是可用于侵袭性真菌感染的最活跃的棘白菌素,因此在医学领域中广泛使用该药物。为了提供与化学、物理、生物学和治疗特性相关的重要参数,这篇综述文章收集了证明该药物生物学潜力的重要研究结果,并介绍了可用于确定抗真菌潜力的分析方法和监测给药剂量。这篇综述文章提供了关于生物活性评估和测定/定量分析方法中最常用方法的重要研究。有了所提供的数据,科学界将有可能选择可用于临床和科学研究的分析方法和生物学,以提供更高的安全性和可靠性的结果。
更新日期:2020-02-16
down
wechat
bug