AIM To explore in a laboratory setting the feasibility of using Meglumine Diatrizoate (MD) to improve the accuracy of diagnosis of cracked teeth on cone-beam CT (CBCT) images. METHODOLOGY Twenty-four teeth were cracked artificially by soaking them cyclically in liquid nitrogen and hot water. The number and position of crack lines were evaluated with a dental operating microscope and used as the gold standard. The artificially cracked teeth were then examined using routine scanning (RS) and enhanced scanning (ES) modes, respectively. For the ES mode, MD was painted on the surface of the crack lines, and then, CBCT scanning with the same parameters was performed after 10 min. A radiological graduate student and an experienced radiologist evaluated the presence or absence of crack lines, respectively. The differences between the RS and ES modes were determined and assessed using McNemar's test. Inter-examiner agreement and intra-examiner agreement were assessed using kappa analysis. RESULTS Fifty-seven crack lines were found in the 24 cracked teeth. In the RS mode, the accuracy of detection of crack lines was 23% (radiological graduate student) and 32% (experienced radiologist), whereas in the ES mode, the accuracy was 61% (radiological graduate student) and 65% (experienced radiologist). The inter-examiner agreement was 0.693 in RS mode and 0.849 in ES mode. The intra-examiner agreement was 0.872 and 0.949 for the radiological graduate student in RS and ES mode respectively; and one for the experienced radiologist both in RS and ES mode. CONCLUSIONS Compared with routine scanning mode, more crack lines could be detected in enhanced scanning mode using Meglumine Diatrizoate as a contrast medium. MD could be a potential contrast medium to improve the accuracy of detection of crack lines on CBCT images.

中文翻译：

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使用Meglumine Diatrizoate来提高锥形束CT图像上牙齿破裂的诊断准确性。

目的在实验室环境中探索使用葡糖重氮酸盐（MD）来提高锥形束CT（CBCT）图像上裂牙诊断的准确性的可行性。方法将二十四颗牙齿周期性地浸泡在液氮和热水中以人工方式使其开裂。用牙科手术显微镜评估裂纹线的数量和位置，并将其用作金标准。然后分别使用常规扫描（RS）和增强扫描（ES）模式检查了人工裂开的牙齿。对于ES模式，将MD涂在裂纹线的表面上，然后在10分钟后执行具有相同参数的CBCT扫描。一名放射学研究生和一名经验丰富的放射科医生分别评估了裂纹线的存在与否。RS和ES模式之间的差异是使用McNemar的测试确定和评估的。使用kappa分析评估检查者间协议和检查者内协议。结果在24颗裂纹的牙齿中发现了57条裂纹线。在RS模式下，裂纹线的检测准确度为23％（放射线研究生）和32％（经验丰富的放射线医师），而在ES模式下，裂纹线的检测准确度为61％（放射线研究生）和65％（经验丰富的放射线医师） ）。审查员之间的协议在RS模式下为0.693，在ES模式下为0.849。放射研究生在RS和ES模式下的检查者内部协议分别为0.872和0.949；一位在RS和ES模式下都适合有经验的放射科医生。结论与常规扫描模式相比，使用泛影酸葡胺作为造影剂，在增强扫描模式下可以检测到更多裂纹线。MD可能是一种潜在的造影剂，可以提高CBCT图像上裂纹线的检测准确性。