Although microvascular proliferation can be observed in glioblastoma, obvious vascularity coupled with coexisting cerebral arteriovenous malformation (AVM) is extremely rare. This report is of a rare case of glioblastoma, coexisting with a cerebral AVM. A 20-year-old male presented with progressive right hemiparesis within 1 month. Cranial magnetic resonance imaging revealed a large bleeding tumor with surrounding dilated vessels. Cerebral angiography demonstrated a left frontal AVM with a 1.2 cm nidus. The patient underwent preoperative embolization and radical resection. The coincidence of glioma and AVM was a rare association. However, the concept of hypervascular glioblastoma has been used in different states from different literature reviews; therefore, the role of proangiogenic factors should be addressed.

中文翻译：

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多形性胶质母细胞瘤与动静脉畸形相关：病例报告和文献综述。

尽管在胶质母细胞瘤中可以观察到微血管增生，但极少见的明显的血管形成与并存的脑动静脉畸形（AVM）并存。该报告是与脑AVM共存的少部分胶质母细胞瘤病例。一名20岁男性在1个月内出现进行性右偏瘫。颅骨磁共振成像显示大出血肿瘤，周围血管扩张。脑血管造影显示左额叶AVM有1.2厘米病灶。患者接受了术前栓塞和根治性切除。胶质瘤和AVM的巧合是罕见的。然而，根据不同的文献综述，在不同的州都使用了高血管胶质母细胞瘤的概念。因此，应探讨促血管生成因子的作用。