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First azole‐resistant Aspergillus fumigatus isolates with the environmental TR 46 /Y121F/ T289A mutation in Iran
Mycoses ( IF 4.1 ) Pub Date : 2020-03-13 , DOI: 10.1111/myc.13064
Fatemeh Ahangarkani 1, 2 , Ynze Puts 2 , Mojtaba Nabili 3 , Sadegh Khodavaisy 4 , Maryam Moazeni 5, 6 , Zahra Salehi 7 , Melika Laal Kargar 7 , Hamid Badali 5, 6, 8 , Jacques F Meis 2, 9
Affiliation  

Azole resistance in Aspergillus fumigatus is an emerging problem and reported from all continents. As triazole antifungals are the mainstay of therapy in the management of invasive aspergillosis, azole‐resistant A fumigatus has become a major medical concern and with complicated clinical management.

中文翻译:

伊朗第一个具有环境 TR 46 /Y121F/ T289A 突变的耐唑类烟曲霉分离株

烟曲霉中的唑类抗性是一个新出现的问题,各大洲都有报道。由于三唑类抗真菌药是侵袭性曲霉病的主要治疗方法,因此耐唑类烟曲霉已成为一个主要的医学问题,并且临床管理复杂。
更新日期:2020-03-13
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