Purpose

Sinusoidal obstruction syndrome (SOS) is one of the most serious complications post haematopoietic stem cell transplantation (HSCT). The diagnosis of SOS is clinical, but nurses should be involved in the pre-transplant risk assessment period and play a crucial role in the early detection of signs and symptoms during and after hospitalization. The aim of this work is to achieve a consensus on nurses’ behaviour in caring for SOS.

Methods

On behalf of the Italian Group for Bone and Marrow Transplantation (GITMO), a promoter committee was established to put in place a consensus conference approach. A multidisciplinary group of GITMO together with four nurses, three haematology physicians and one patient representative acted as jury, who reviewed the reports and wrote recommendations and suggestions. Recommendations gaining 100% of consensus were considered ‘Golden Points of Care’; if a consensus was achieved by ≥ 75% of the jury’s members, those recommendations were defined as ‘Good Practices’.

Results

Eighteen papers written by nurses as first authors have been identified. Golden Points of Care and Good Practices were worked out for the following topics: nurses’ role in general, nurses’ role in pre-transplant assessment, pre-transplant risk assessment and risk stratification, baseline monitoring, suspected mild or moderate SOS, suspected severe or very severe SOS and late-onset cases.

Conclusion

SOS is relatively rare; therefore, a holistic approach to the patients’ needs considering nursing role as essential may result in better care outcomes.

中文翻译：

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在肝窦窦阻塞综合征患者评估和护理中的护理作用：“ Gruppo Italiano Trapianto di Midollo Osseo”的共识性论文。

目的

窦性阻塞综合征（SOS）是造血干细胞移植（HSCT）后最严重的并发症之一。SOS的诊断是临床性的，但护士应参与移植前的风险评估期，并在住院期间和之后的早期发现体征和症状中发挥关键作用。这项工作的目的是就护士在照顾SOS方面的行为达成共识。

方法

代表意大利骨和骨髓移植小组（GITMO）成立了发起人委员会，以制定共识性会议方法。GITMO的一个多学科小组与四名护士，三名血液学医师和一名患者代表一起担任陪审团，他们评审了报告并提出了建议和建议。获得100％共识的建议被视为“黄金护理要点”；如果评审委员会成员中有≥75％达成共识，则将这些建议定义为“良好做法”。

结果

确定了由护士作为第一作者的18篇论文。针对以下主题制定了“黄金护理要点和良好做法”：护士的一般角色，护士在移植前评估，移植前风险评估和风险分层，基线监测，疑似轻度或中度SOS，疑似重症的作用或非常严重的SOS和迟发病例。

结论

SOS相对较少；因此，将护理角色视为必不可少的整体方法来满足患者的需求，可能会带来更好的护理效果。