BACKGROUND Different dementia syndromes display different patterns of everyday functioning. This article explored different patterns of functioning at baseline and trajectories of change in behavioral variant frontotemporal dementia (bvFTD) and Alzheimer disease (AD). METHODS Data from the Uniform Data Set of the National Alzheimer's Coordinating Centre were employed. The Functional Assessment Questionnaire assessed functioning at up to 7 follow-up visits. Independent t tests assessed variations in functioning between syndromes at baseline. Linear mixed-effect modeling explored longitudinal functional trajectories between syndromes. RESULTS Data from 3351 patients (306 bvFTD and 3,045AD) were analyzed. At baseline, patients with bvFTD performed all daily activities poorer than AD dementia. Linear mixed models showed a significant effect of syndrome and time on functioning, and evidence of interaction between syndrome and time, with bvFTD showing a steeper decline for using the stove and travel. CONCLUSIONS Findings can help in the effective care planning of everyday functioning for bvFTD and AD dementia.

中文翻译：

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通过日常功能概况区分额颞叶痴呆和阿尔茨海默病：变化轨迹。

背景技术不同的痴呆综合征表现出不同的日常功能模式。本文探讨了不同的基线功能模式和行为变异额颞叶痴呆 (bvFTD) 和阿尔茨海默病 (AD) 的变化轨迹。方法 使用来自国家阿尔茨海默病协调中心统一数据集的数据。功能评估问卷在多达 7 次随访中评估了功能。独立 t 检验评估基线综合征之间的功能变化。线性混合效应模型探索了综合征之间的纵向功能轨迹。结果 分析了来自 3351 名患者（306 名 bvFTD 和 3,045 名 AD）的数据。在基线时，bvFTD 患者的所有日常活动都比 AD 痴呆差。线性混合模型显示症状和时间对功能的显着影响，以及症状和时间之间相互作用的证据，bvFTD 显示使用炉子和旅行的下降幅度更大。结论 研究结果有助于对 bvFTD 和 AD 痴呆的日常功能进行有效的护理规划。