ABSTRACT Relationships between neurodevelopmental functioning and hemodynamic changes in the prefrontal cortex (PFC) were contrasted between children with prenatal alcohol exposure (PAE) and children who differed relative to their history of PAE and the presence of other neurodevelopmental impairment. For all groups, deoxygenated hemoglobin (HBR) levels in the medial PFC area were negatively related to externalizing problems and levels in the medial and right lateral PFC were positively related to errors on a cognitive inhibition task. Hemodynamic changes in the medial and right lateral PFC of children with PAE demonstrated stronger relationships to aspects of executive functioning relative to contrast groups.

中文翻译：

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与胎儿酒精谱系障碍儿童的前额叶皮层脱氧相关的神经发育结果

摘要 在产前酒精暴露 (PAE) 的儿童和相对于其 PAE 病史和其他神经发育障碍的存在不同的儿童之间，对比了神经发育功能和前额叶皮层 (PFC) 血流动力学变化之间的关系。对于所有组，内侧 PFC 区域的脱氧血红蛋白 (HBR) 水平与外化问题呈负相关，内侧和右侧 PFC 的水平与认知抑制任务的错误呈正相关。与对照组相比，PAE 儿童内侧和右侧 PFC 的血流动力学变化表明与执行功能方面的关系更强。