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Paeniclostridium (Clostridium) sordellii-associated enterocolitis in 7 horses.
The Journal of Veterinary Diagnostic Investigation ( IF 1.5 ) Pub Date : 2020-02-13 , DOI: 10.1177/1040638720903738
Akinyi C Nyaoke 1, 2 , Mauricio A Navarro 1, 2 , Karina Fresneda 1, 2 , Santiago S Diab 1, 2 , Janet Moore 1, 2 , Dena Lyras 1, 2 , Milena Awad 1, 2 , Francisco A Uzal 1, 2
Affiliation  

Enteric disease in horses may be caused by a variety of microorganisms, including several clostridial species. Paeniclostridium sordellii (previously Clostridium sordellii) has been frequently associated with gas gangrene in humans and several animal species, including horses. However, its role in enteric diseases of animals has not been fully determined. We describe herein 7 cases of enteric disease in horses associated with P. sordellii infection. Grossly, the small and/or large intestines were necrotic, hemorrhagic, and edematous. Microscopically, there was severe mucosal necrosis and hemorrhage of the small and/or large intestine of all horses. P. sordellii was isolated and/or demonstrated by immunohistochemistry and/or PCR in the intestine of all horses. All other known causes of enteric disease in horses were ruled out in these 7 cases. P. sordellii should be considered among the differential diagnoses in cases of enteric disease in horses.

中文翻译:

7匹马中的Paeniclostridium(Clostridium)索氏菌相关小肠结肠炎。

马的肠道疾病可能是由多种微生物引起的,包括几种梭菌。Paeniclostridium sordellii(以前称为Clostridium sordellii)在人类和包括马在内的几种动物中经常与气体坏疽有关。然而,其在动物肠道疾病中的作用尚未完全确定。我们在本文中描述了7例与Sodellii感染相关的马肠道疾病。总体而言,小肠和/或大肠坏死,出血和水肿。在显微镜下,所有马的小肠和/或大肠均存在严重的粘膜坏死和出血。通过免疫组织化学和/或PCR在所有马的肠中分离和/或证实了索德氏疟原虫。在这7例病例中,排除了其他所有已知的引起马肠道疾病的原因。P.
更新日期:2020-02-13
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