Sixty-nine dyads of patients with Alzheimer's disease and primary caregivers have been followed up for 1 year to evaluate cognitive (Mini-Mental State Examination), functional (Instrumental Activities of Daily Living), and behavioral (Neuropsychiatric Inventory) decline of patient in relation to burden (Caregiver Burden Inventory), stress (Relative Stress Scale), anxiety (State-Trait Anxiety Inventory Y), and depression (Beck Depression Inventory) reported by the caregivers. After 1 year of observation, cognitive and functional scores worsened while behavioral problems remained unchanged and relatively mild in patients. After 1 year, caregivers' scores of scales of anxiety and depression decreased significantly, while stress scores remained unchanged and burden slightly increased. In our opinion, the unexpected improvement in psychological situation of caregivers may be mainly due to educational interventions focused on knowledge of the disease with a particular attention directed toward emotional support and individual needs.

中文翻译：

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焦虑和抑郁与阿尔茨海默氏病患者的照护者负担和压力的增加无关。

随访了69名患阿尔茨海默氏病和初级护理人员的二联症，为期一年，以评估患者的认知能力（小精神状态检查），功能（日常生活的工具活动）和行为（神经精神病学库存）下降的相关性照料者报告的负担（照料者负担清单），压力（相对压力量表），焦虑（状态-特质焦虑量表Y）和抑郁（贝克抑郁量表）。经过1年的观察，患者的认知和功能评分恶化，而行为问题保持不变且相对较轻。一年后，护理人员的焦虑和抑郁量表得分显着下降，而压力得分保持不变，负担略有增加。在我们看来，