This issue of the ILAR Journal focuses on the topic of responsible science as it relates to animal research. We start with the concept of the scientist as a responsible citizen and then move through multiple phases of research including careful experimental planning, reporting, and incorporation of laboratory animal science. The work of the Institutional Animal Care and Use Committee (IACUC) or animal ethical/oversight body in reviewing both animal use and contributing to scientific excellence is explored. Additional topics include protection of animal handlers from multiple experimental hazards, use of agricultural animals and wildlife studies, regulatory ambiguities, and harmonization of animal research. Rounding out the issue is a discussion of how animal care and use programs can enhance animal welfare while mitigating regulatory burden, and our responsibility to clearly communicate the ethical use of animals in advancing biomedical research. A deeper understanding of these topics can assist scientists in simultaneously advancing their research and animal welfare.

中文翻译：

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负责任的科学研究和动物使用。

本期《 ILAR杂志》关注与动物研究相关的负责任科学主题。我们从科学家作为负责任的公民的概念开始，然后进入研究的多个阶段，包括仔细的实验​​计划，报告和实验室动物科学的纳入。探索了机构动物护理和使用委员会（IACUC）或动物伦理/监督机构在审查动物使用和促进科学卓越方面的工作。其他主题包括保护动物从业者免受多重实验危害，使用农业动物和野生动植物进行研究，法规上的歧义以及动物研究的协调统一。解决问题的方法是讨论动物护理和使用计划如何在减轻监管负担的同时提高动物福利，以及在推进生物医学研究中明确传达动物的道德使用责任。对这些主题的更深刻理解可以帮助科学家同时推进其研究和动物福利。