During development, Cajal‐Retzius (CR) cells are the first generated and essential pioneering neurons that control neuronal migration and arealization in the mammalian cortex. CR cells are derived from specific regions within the telencephalon, that is, the pallial septum in the rostromedial cortex, the pallial‐subpallial boundary, and the cortical hem (CH) in the caudomedial cortex. However, the molecular mechanism underlying the generation of CR cell subtypes in distinct regions of origin is poorly understood.

中文翻译：

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Dmrt基因参与了源于端脑皮质下摆的Cajal-Retzius细胞的发育。

在发育过程中，Cajal-Retzius（CR）细胞是控制哺乳动物皮质中神经元迁移和区域化的第一个生成且必不可少的神经元。CR细胞来自于末梢脑内的特定区域，即，在前额皮质中的睑板间隔，丘脑-睑下边界和在颞内侧皮质的皮质下摆（CH）。但是，对在起源的不同区域中产生CR细胞亚型的分子机制了解甚少。