PURPOSE We aimed to evaluate the risk factors of focal involvement in brucellosis. METHODS The data of brucellosis patients were analyzed retrospectively from 2010 through 2019. Patients were divided into two groups: focal involvement (-) and focal involvement (+). The clinical findings, complications and laboratory findings of patients were compared between the two groups. RESULTS Two hundred thirty patients were included in the study. One hundred twenty-seven of the patients (55.2%) were male and mean age was 45.8 ± 17.1 (16-86) years. Focal involvement was observed in 98 (42.6%) patients. The variables that differed significantly between groups were age (P < 0.001), fever (P = 0.016), back pain (P < 0.001), leukocyte (P = 0.012), neutrophil (P = 0.004), platelet (P = 0.002), mean platelet volume (MPV) (P = 0.043) and erythrocyte sedimentation rate (ESR) (P = 0.001). Older age (>45 years) and back pain were found to be independent risk factors for predicting focal involvement (P = 0.036 and P < 0.001). CONCLUSIONS The clinical findings and markers that are significant in determining focal involvement may be useful in identifying complicated brucellosis.

中文翻译：

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布鲁氏菌病病灶参与的危险因素。

目的我们旨在评估布鲁氏菌病病灶参与的危险因素。方法回顾性分析2010年至2019年布鲁氏菌病患者的数据。将患者分为两组：病灶受累（-）和病灶受累（+）。比较两组患者的临床表现，并发症和实验室检查结果。结果本研究纳入了233例患者。一百二十七名患者（55.2％）是男性，平均年龄为45.8±17.1（16-86）岁。98例（42.6％）患者发生局灶性受累。各组之间的差异显着不同是年龄（P <0.001），发烧（P = 0.016），背痛（P <0.001），白细胞（P = 0.012），中性粒细胞（P = 0.004），血小板（P = 0.002） ，平均血小板体积（MPV）（P = 0。043）和红细胞沉降率（ESR）（P = 0.001）。发现年龄较大（> 45岁）和背部疼痛是预测病灶受累的独立危险因素（P = 0.036和P <0.001）。结论在确定局灶受累中具有重要意义的临床发现和标志物可能对鉴别复杂的布鲁氏菌病有用。