Globally, coinfection of human immunodeficiency virus (HIV) patients with Hepatitis B Virus (HBV) is associated with an accelerated progression of HIV disease and higher mortality resulting from complications of liver-related disease. Despite the public health importance, data are lacking on this subject in the study area. Therefore, we evaluated the prevalence and risk factors for HIV/HBV coinfection among HIV patients accessing antiretroviral treatment in Lokoja, Nigeria. In a cross-sectional study, sera from randomly selected 200 consenting HIV patients were screened for hepatitis B surface antigen (HBsAg) using The Commercial Rapid Immunoassay Test Kit. Demographic variables and putative risk factors of HBV transmission were obtained using structured questionnaire. HBsAg prevalence was 8.0% in the sampled group with higher seropositivity rate in the age group, 40–49 years, followed by those 20–29 years of age, whereas the other age groups had zero positivity rates each. The difference between seroprevalence rates in relation to patients' age and sex was not statistically significant (p > 0.05). Patients with no formal education, who were married and were housewives, had higher rates of HBV infection compared with others in the group. Although not statistically significant (p > 0.05), the likelihood of exposure to HBV was higher among patients who were engaged in multiple sexual behaviors, alcoholism, smoking, sharing of sharps, ear piercing, and had history of blood transfusion. Conclusively, HIV/HBV coinfection rate in our study is comparable to other localities and thus, affirm the endemicity in the study area. The need to strengthen health education of the masses to desist from risky behaviors is recommended to reduce the morbidity and mortality arising from HIV/HBV comorbidity.

中文翻译：

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在尼日利亚中北部的洛科贾，人类免疫缺陷病毒感染的乙型肝炎病毒患者的合并感染。

在全球范围内，人类免疫缺陷病毒（HIV）患者与乙型肝炎病毒（HBV）合并感染与HIV疾病的加速发展和由于与肝脏相关疾病的并发症导致的更高死亡率相关。尽管具有公共卫生重要性，但研究区域中缺乏有关该主题的数据。因此，我们评估了在尼日利亚洛科贾接受抗逆转录病毒治疗的HIV患者中HIV / HBV合并感染的患病率和危险因素。在一项横断面研究中，使用商业快速免疫测定试剂盒对随机选择的200名HIV同意者的血清进行了乙型肝炎表面抗原（HBsAg）筛查。使用结构化问卷调查获得了HBV传播的人口统计学变量和推定的危险因素。HBsAg患病率为8。在年龄段为40-49岁的人群中，血清阳性率较高的人群为0％，其次为20-29岁的人群，而其他年龄组的阳性率均为零。血清阳性率与患者年龄和性别之间的差异无统计学意义（p  > 0.05）。与未受过正规教育的已婚患者和家庭主妇相比，该组患者的HBV感染率更高。尽管没有统计学意义（p  > 0.05），但是在患有多种性行为，酗酒，吸烟，尖锐，耳穿孔和有输血史的患者中，接触HBV的可能性更高。结论是，我们研究中的HIV / HBV合并感染率与其他地区相当，因此肯定了研究区域的流行性。建议减少大众的健康教育，以防止危险行为，以减少艾滋病毒/乙肝合并症的发病率和死亡率。