Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is a debilitating condition that affects 0.2–0.4% of the population. Health focussed anxiety is common across medical conditions, and may be relevant in CFS/ME. This study sought to identify the prevalence and impact of health anxiety (HA) in CFS/ME and evaluate the effectiveness of Cognitive Behavioural Therapy for HA in CFS/ME. Cross-sectional questionnaire methods and case-series design were used to achieve study aims. Analysis indicated that 41.9% of the CFS/ME clinic sample experienced threshold levels of health anxiety, which was associated with elevated symptom severity across several dimensions. Stepwise multiple regression indicated physical functioning and depression accounted for 23.8% of variance in fatigue; depression, fatigue and HA, accounted for 32.9% of variance in physical functioning. Large effect sizes and clinically significant changes were generated in the treatment study. HA is common in CFS/ME and likely to exacerbate fatigue and physical functioning. This study identifies HA as an important target for treatment, trial findings should be further replicated on a larger scale.

慢性疲劳综合症/肌性脑脊髓炎（CFS / ME）是一种使人衰弱的疾病，影响了0.2％至0.4％的人口。以健康为中心的焦虑症在医疗条件中很常见，在CFS / ME中可能与此有关。这项研究试图确定CFS / ME中健康焦虑症（HA）的患病率和影响，并评估CFS / ME中HA认知行为疗法的有效性。横断面调查问卷方法和案例系列设计用于实现研究目的。分析表明，CFS / ME临床样本的41.9％经历了健康焦虑的阈值水平，这与在多个维度上症状严重性升高相关。逐步多元回归表明，身体功能和抑郁占疲劳差异的23.8％；抑郁，乏力和HA，占32。身体机能差异的9％。在治疗研究中产生了大的效应量和临床上显着的变化。HA在CFS / ME中很常见，并且可能加剧疲劳和身体机能。这项研究确定HA是治疗的重要靶标，试验结果应进一步大规模复制。