Background: Parkinson´s disease (PD) and depression have an interplay at multiple cellular levels, a phenomenon which is translated into clinical data showing that depressive patients presented an enhanced risk for developing PD. The pathogenesis of both diseases is under intensive debate as correlated to dysregulations related to Ca2+ signaling.

Objective: Then, revealing this interplay between these diseases may provide novel insights into the pathogenesis of them.

中文翻译：

---

抑郁症和帕金森氏病之间的相互作用：通过Ca2 + / cAMP信号传导学习联系。

背景：帕金森氏病（PD）和抑郁症在多个细胞水平上相互作用，这种现象转化为临床数据，表明抑郁症患者罹患PD的风险增加。两种疾病的发病机理都与与Ca2 +信号传导有关的调节异常有关，目前正在激烈辩论中。

目的：然后，揭示这些疾病之间的相互作用可能为它们的发病机理提供新颖的见解。