Hormones such as estrogen, progesterone, and aldosterone all demonstrate vital roles in sustaining auditory function through either the maintenance of cochlear neurons, up/down regulation of critical molecules (i.e., IGF‐1, BDNF, etc.), or generation of the endocochlear potential. With disease and/or age, hormone expression begins to decline drastically, which ultimately affects cochlear structures and the integrity of cochlear cells. The following review explores the latest findings as well as realistic outcomes for hormone therapy treatment in the auditory system. This information could serve as a potential guide for patients considering hormone therapy as a medicinal choice to alleviate the signs of onset of presbycusis—age‐related hearing loss. Additional scientific investigations could also be carried out to further enhance recent findings.

中文翻译：

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了解激素和激素疗法对听觉系统的影响。

雌激素、黄体酮和醛固酮等激素都通过维持耳蜗神经元、关键分子（即 IGF-1、BDNF 等）的上调/下调或内耳蜗的产生，在维持听觉功能方面发挥着重要作用。潜在的。随着疾病和/或年龄的增长，激素表达开始急剧下降，最终影响耳蜗结构和耳蜗细胞的完整性。以下综述探讨了听觉系统激素治疗的最新发现和现实结果。该信息可作为考虑将激素治疗作为减轻老年性耳聋（与年龄相关的听力损失）发病迹象的药物选择的患者的潜在指南。还可以进行额外的科学调查，以进一步加强最近的发现。