Transfer RNA (tRNA) is the central intellectual property in the evolution of life on Earth. tRNA evolved from repeats and inverted repeats of known sequence. The anticodon and the T stem-loop-stems are homologs with significant conserved sequence identity. A number of models have been advanced to explain tRNA evolution. No 2-minihelix model or accretion model (built a stem at a time) can be correct, in part because of anticodon and T stem-loop-stem identity. Only a 3-minihelix model is adequate.

中文翻译：

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3-Minihelix tRNA进化定理。

转移RNA（tRNA）是地球生命进化的核心知识产权。tRNA由已知序列的重复和反向重复演变而来。反密码子和T茎-环-茎是具有显着保守的序列同一性的同源物。已经开发了许多模型来解释tRNA的进化。2-minihelix模型或增生模型（一次建立一个茎）是不正确的，部分原因是因为反密码子和T茎-环-茎同一性。仅3微螺旋模型已足够。