Positive Aspergillus PCR as a marker of azole resistance or sub‐therapeutic antifungal therapy in patients with chronic pulmonary aspergillosis,Mycoses

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Positive Aspergillus PCR as a marker of azole resistance or sub‐therapeutic antifungal therapy in patients with chronic pulmonary aspergillosis
Mycoses ( IF 4.1 ) Pub Date : 2020-04-01 , DOI: 10.1111/myc.13052
Samihah Moazam _{1,

2} , Christopher Philip Eades _{1,

2} , Eavan Gabrielle Muldoon _{1,

2} , Caroline B Moore _{2,

3} , Malcolm D Richardson _{2,

3} , Riina Rautemaa-Richardson _{1,

2,

3}

Affiliation

Chronic pulmonary aspergillosis (CPA) is a progressive respiratory disease, caused most commonly by A fumigatus, with significant morbidity and mortality. Azole resistance in A fumigatus is a growing concern worldwide, with resistance to itraconazole reported in up to 50% of patients.

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