Oral defense should be able to sense the burden of, and distinguish between fungal commensals and pathogens, so that an adequate inflammatory response can be set up. Recently, Ephrin type-A receptor 2 (EphA2) was identified on oral epithelial cells and neutrophils that recognizes Candida albicans and induces adaptive protective host responses against this organism. The studies have increased our knowledge of how epithelial cells and neutrophils contribute to host defense against oral yeast infection.

中文翻译：

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EphA2在宿主预防口咽念珠菌病中的作用。

口腔防御应该能够感知真菌的负担和病原体的负担，并对其进行区分，以便可以建立足够的炎症反应。最近，在口腔上皮细胞和嗜中性粒细胞中鉴定出了Ephrin A型受体2（EphA2），它识别白色念珠菌并诱导针对该生物的适应性保护性宿主反应。这些研究增加了我们对上皮细胞和嗜中性粒细胞如何有助于宿主防御口腔酵母菌感染的知识。