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Protective effects of melatonin on male fertility preservation and reproductive system
Cryobiology ( IF 2.3 ) Pub Date : 2020-08-01 , DOI: 10.1016/j.cryobiol.2020.01.018
Tie-Cheng Sun 1 , Hui-Ying Li 2 , Xiao-Yu Li 3 , Kun Yu 4 , Shou-Long Deng 5 , Li Tian 6
Affiliation  

Melatonin is a ubiquitous indoleamine hormone synthesized primarily by the pineal gland. Diverse biological actions of melatonin involve quite complex mechanisms via its membrane receptors. More recently, studies have focused on the role of melatonin in male fertility preservation and male reproductive system. The protective effects of melatonin on immature testicular tissue freshness and activity maintenance and the preservation of sperm and spermatogonial stem cells (SSCs) have attracted considerable attention in recent years. Furthermore, since melatonin has strong antioxidant and anti-apoptotic properties, researchers have examined its potential role in male reproductive system. In this article, recent progress regarding melatonin's effects on male fertility preservation and its potential role is reviewed.

中文翻译:

褪黑激素对男性生育力保存和生殖系统的保护作用

褪黑激素是一种普遍存在的吲哚胺激素,主要由松果体合成。褪黑激素的多种生物作用通过其膜受体涉及相当复杂的机制。最近,研究集中在褪黑激素在男性生育能力保护和男性生殖系统中的作用。近年来,褪黑激素对未成熟睾丸组织新鲜度和活性维持以及精子和精原干细胞(SSCs)保存的保护作用引起了广泛关注。此外,由于褪黑激素具有很强的抗氧化和抗凋亡特性,研究人员已经研究了它在男性生殖系统中的潜在作用。本文综述了褪黑激素对男性生育力保存的影响及其潜在作用的最新进展。
更新日期:2020-08-01
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