HIV+ persons have a significantly increased risk of cancer when compared to the general population. The excess cancer risk observed during HIV infection is particularly higher for infection-related malignancies. Mechanisms underlying this remain unclear, but both HIV-related and HIV-unrelated factors have been postulated to play a role. Here, we (i) review newly published data on cancer burden in the setting of HIV infection with a focus on HIV-related risk factors for cancer; (ii) discuss emerging data on cancer among HIV+ persons living in low- and middle-income countries; and (iii) review guideline recommendations for cancer screening among HIV+ persons and discuss ongoing studies investigating strategies for cancer screening among HIV+ patients.

中文翻译：

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HIV感染期间的癌症。

与普通人群相比，HIV +人群罹患癌症的风险显着增加。对于感染相关的恶性肿瘤，在HIV感染期间观察到的过量癌症风险尤其高。造成这种情况的机制尚不清楚，但已假定与艾滋病毒有关和与艾滋病毒无关的因素都在发挥作用。在这里，我们（i）回顾了有关HIV感染情况下癌症负担的新发表数据，重点是与HIV相关的癌症危险因素；（ii）讨论生活在中低收入国家的艾滋病毒+感染者中有关癌症的新数据；（iii）审查关于在HIV +患者中进行癌症筛查的指南建议，并讨论正在进行的研究，以研究在HIV +患者中进行癌症筛查的策略。