Rift Valley Fever (RVF) is an emerging zoonotic arbovirus with a complex cycle of transmission that makes difficult the prediction of its expansion. Recent outbreaks outside Africa have led to rediscover the human disease but it remains poorly known. The wide spectrum of acute and delayed manifestations with potential unfavorable outcome much complicate the management of suspected cases and prediction of morbidity and mortality during an outbreak. We reviewed literature data on bio-clinical characteristics and treatments of RVF human illness. We identified gaps in the field and provided a practical algorithm to assist clinicians in the cases assessment, determination of setting of care and prolonged follow-up.

中文翻译：

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裂谷热在人类中的挑战性管理：临床疾病和算法建议的文献综述。

裂谷热（RVF）是一种新兴的人畜共患虫病毒，具有复杂的传播周期，因此很难预测其扩展。非洲以外最近爆发的疫情重新发现了人类疾病，但人们对其知之甚少。范围广泛的急性和迟发性表现以及潜在的不利结果，大大增加了可疑病例的管理以及疾病暴发期间发病率和死亡率的预测。我们回顾了有关RVF人类疾病的生物临床特征和治疗的文献数据。我们确定了该领域的差距，并提供了一种实用的算法来协助临床医生进行病例评估，确定护理设置和长期随访。