This manuscript is a review focused onto the role of astrocytes in the protection of neurons against oxidative stress and how melatonin can contribute to the maintenance of brain homeostasis. The first part of the review is dedicated to the dependence of neurons on astrocytes by terms of survival under oxidative stress conditions. Additionally, the effects of melatonin against oxidative stress in the brain and its putative role in the protection against diseases affecting the brain are highlighted. The effects of melatonin on the physiology of neurons and astrocytes also are reviewed.

中文翻译：

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脑生理学中的抗氧化剂和神经元-星形胶质细胞相互作用：褪黑激素，一个值得依赖的邻居。

这篇手稿是一篇评论，重点是星形胶质细胞在保护神经元免受氧化应激中的作用，以及褪黑激素如何有助于维持脑内稳态。评论的第一部分致力于通过氧化应激条件下的存活率来研究神经元对星形胶质细胞的依赖性。此外，还强调了褪黑激素对大脑氧化应激的作用及其在预防影响大脑的疾病方面的假定作用。褪黑激素对神经元和星形胶质细胞生理的影响也进行了综述。